Jesse Rowley

Jesse Rowley, PhD is a Principal Investigator at the University of Utah School of Medicine, Department of Internal Medicine. His research focuses on understanding how platelets and megakaryocytes influence human health and disease through integration of multi-omics approaches with traditional molecular, cellular, and in vivo methodologies.

Dr. Rowley's educational background includes:

• PhD from The Johns Hopkins University
• BS from Brigham Young University
• Postdoctoral Fellowship at The Johns Hopkins University
• Postdoctoral Research Fellow at University of Utah

Dr. Rowley's research interests center on platelet and megakaryocyte biology, with a focus on understanding the molecular mechanisms that govern platelet function in health and disease. His work integrates cutting-edge transcriptomic approaches with traditional molecular and cellular techniques to uncover new diagnostic and therapeutic avenues for platelet-related disorders. His laboratory has made significant contributions to understanding mitochondrial dynamics in platelets, the platelet transcriptome in various disease states, and developing innovative CRISPR-based approaches for studying platelet gene function.

Analysis of Dr. Rowley's recent publications reveals a strong focus on platelet biology, particularly examining mitochondrial dynamics, transcriptomic changes in disease states, and innovative gene editing approaches. His work spans multiple disciplines including hematology, immunology, cardiovascular biology, and molecular genetics, with particular emphasis on how platelet dysfunction contributes to conditions like sepsis, thrombosis, autoimmune disorders, and viral infections including COVID-19.

Dr. Rowley leads the Rowley Laboratory in Salt Lake City, Utah, which focuses on understanding platelet and megakaryocyte function through clinical discovery and advanced molecular, cellular, in vivo, and computational approaches. The lab has developed innovative techniques such as CRIMSON (CRISPR-edited Megakaryocytes for rapid Screening of platelet gene functiON) for studying platelet gene function.