Jesper M. Mathiesen

Jesper M. Mathiesen is an Associate Professor in the Department of Drug Design and Pharmacology within the Faculty of Health and Medical Sciences at the University of Copenhagen. His research focuses on molecular and cellular pharmacology, particularly studying G-protein coupled receptors (GPCRs) and their modulation mechanisms.

Dr. Mathiesen's research interests include:

• Molecular mechanisms of G-protein coupled receptor signaling
• Allosteric modulation of calcium-sensing receptors
• Pharmacology of opioid receptors and development of novel therapeutics
• Structure-function relationships of receptors
• Drug design targeting receptor systems
• Nanobody applications in receptor pharmacology

His recent publications demonstrate significant contributions to understanding receptor pharmacology, with work appearing in high-impact journals including Nature. His research shows particular expertise in calcium-sensing receptors and opioid receptor systems, with implications for treating disorders related to calcium homeostasis and developing improved pain management therapies with reduced addiction potential.

Dr. Mathiesen has received considerable attention for his work, with several publications picked up by numerous news outlets (one paper by 83 news outlets) and referenced in academic platforms including Wikipedia. His collaborative network includes prominent researchers such as Nobel laureate Brian Kobilka.