Jeffrey R. Millman

Jeffrey R. Millman is Professor of Medicine and Biomedical Engineering at Washington University. His lab develops stem cell-derived pancreatic β cells for diabetes treatment, creating functional SC-β cells that reverse hyperglycemia in mice. Research combines biomedical engineering with stem cell biology to improve cell differentiation protocols.

Key Achievements:

• Developed 6-step protocol for functional SC-β cell generation
• Produced scalable suspension cultures (500M cells/batch)
• Demonstrated diabetes reversal in mouse models

Research Focus: Microenvironmental optimization of β cell differentiation, disease modeling using diabetic patient-derived iPSCs, and clinical translation of cell therapies.