Jay S. Skyler

Jay S. Skyler, Professor in the Department of Medicine, specializes in Endocrinology, Diabetes, and Metabolism. His research focuses on the genetic and immunological mechanisms of type 1 diabetes progression, particularly in clinical trials like DPT-1 and TN07.

Education:

• 1969: Jefferson Medical College (MD)

His work explores the role of HLA class II genes in autoimmunity and ß-cell function decline. Recent studies analyze biomarkers such as C-peptide and Index60 to refine diabetes staging criteria and risk assessment.

Publications highlight trends in type 1 diabetes prevention, emphasizing genetic susceptibility and metabolic impairments in early disease phases. Collaborative efforts include consensus guidelines for adult diabetes management.