Jason Tchieu

Dr. Jason Tchieu is a researcher at the University of Cincinnati, affiliated with a laboratory studying human pluripotent stem cells (hPSCs). His work focuses on leveraging hPSCs to model neurodevelopment and investigate disease mechanisms.

Research Interests: Dr. Tchieu's research explores the differentiation of hPSCs into specific cell types, particularly within the ectodermal lineage and neuroectoderm. Key projects include:

• Developing strategies to generate the entire ectodermal lineage, identifying how subtle growth factor changes influence cell fate.
• Investigating the neurogenic-to-gliogenic switch during human neural development, achieving accelerated astrocyte differentiation from hPSC-derived neural stem cells (NSCs).

His findings aim to advance therapies for neurodevelopmental disorders by enabling in vitro disease modeling and functional cell generation.