Jane Zhu

Dr. Jane Zhu is an Associate Professor of Biochemistry and Molecular Biology at Mayo Clinic, with a joint appointment in Molecular Pharmacology and Experimental Therapeutics. She leads a laboratory focused on neuroblastoma pathogenesis, tumor metastasis, and phosphatase signaling in cancers. Her work uses functional genomics and zebrafish models to translate genetic findings into therapies. Dr. Zhu holds a MD/Pediatrics from Norman Bethune University of Medical Sciences and a PhD in Cell Signaling and Developmental Biology from National University of Singapore. She completed a postdoctoral fellowship in Cancer Biology at Dana-Farber Cancer Institute/Harvard Medical School.

• Education:
  • Postdoctoral Fellowship: Dana-Farber Cancer Institute, Harvard Medical School
  • PhD: National University of Singapore
  • MMSc: Jilin University Medical School
  • MD: Norman Bethune University of Medical Sciences
• Research Focus:
  • Neuroblastoma pathogenesis mechanisms
  • Zebrafish models of metastasis
  • Phosphatase signaling pathways in tumors

Her research has been recognized through awards such as the NIH Pathway to Independence Award and multiple foundation grants. Dr. Zhu's lab collaborates on projects funded by the Department of Defense and the V Foundation. Recent work includes defining tumor-suppressor roles of PTPRD and exploring LMO1/MYCN cooperation in metastasis using novel zebrafish models.

• Key Projects:
  • Role of PTPRD as a tumor suppressor (ongoing)
  • Zebrafish model of neuroblastoma metastasis
• Awards:
  • 7 major research grants and fellowships since 2012

Her lab's findings aim to reduce neuroblastoma mortality through molecular insights and targeted therapies.