About
Jan Tytgat is a full Professor at KU Leuven, affiliated with the Faculty of Pharmaceutical Sciences and the Department of Pharmaceutical and Pharmacological Sciences. He leads the Unit of Toxicology and Pharmacology, focusing on ion channels, venom peptides, and drug discovery.
- Faculty of Pharmaceutical Sciences, KU Leuven
- Unit of Toxicology and Pharmacology
- Division Biopharmaceutical Sciences
Research Interests: Jan Tytgat's work centers on pharmacological characterization of toxins from animal venoms, particularly targeting ion channels (e.g., TRPV1, Nav1.5, KV1.x) for drug development. His studies span endometrial cancer, cardiovascular diseases, and venom-induced inflammation.
Publication Trends: Recent articles emphasize venom-derived peptides (spider, scorpion, sea anemone, stonefish) as tools for studying ion channels and developing therapeutics. Topics include toxin selectivity, molecular engineering, and novel applications in neuropharmacology and oncology.
Labs & Teams: He coordinates research in the Toxicology and Pharmacology unit, supervises projects on venom peptides, and collaborates with international networks like Biodiversity2Drugs Consortium.
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