Jan Benada

Jan Benada is an Academic employee at the University of Copenhagen's Biotech Research & Innovation Centre (BRIC), working within the Sørensen Group led by C.S. Sørensen. Based at Ole Maaløes Vej 5 in Copenhagen, he conducts cutting-edge research at the intersection of molecular biology and cancer therapeutics with significant contributions to understanding genome maintenance mechanisms.

His research focuses on the intricate relationship between DNA repair pathways and cancer development, with particular expertise in:

• Genome integrity and tumor suppression mechanisms
• Molecular adaptations of cancer cells to genotoxic stress
• Cell cycle regulation through WEE1 kinase and related pathways
• Synthetic lethal interactions as therapeutic targets
• Molecular basis of ovarian and breast carcinomas

Dr. Benada's publication record demonstrates consistent high-impact output, with multiple first-author papers in prestigious journals including Science and The Journal of Clinical Investigation. His 2022 Science paper on cancer cells using self-inflicted DNA breaks has received substantial attention with 53 Scopus citations and coverage by 15 news outlets. His work shows particular strength in translating basic molecular discoveries into potential therapeutic applications, as evidenced by his research on WEE1-PKMYT1 interactions in ovarian cancer.

Dr. Benada maintains extensive collaborative networks both within the University of Copenhagen and internationally, working with researchers across multiple disciplines including molecular biology, clinical oncology, and proteomics. His research has been highlighted across various platforms including news outlets, social media (with one paper mentioned by 284 X users), and academic platforms like Mendeley.