About
James Whitney is a Research Professor in the Department of Biology at Boston College. His work focuses on preclinical non-human primate models for vaccines and immunotherapeutics targeting cancer and infectious diseases, particularly HIV and SIV. Utilizing rhesus and cynomolgus macaques, he investigates immune responses, viral reservoir dynamics, and novel therapeutic strategies.
- Ph.D. from McGill University
- Core research: HIV/SIV vaccine development and immunotherapy
Research interests span multiple disciplines:
- Vaccinology (targeting protease cleavage sites)
- Immunotherapy (checkpoint inhibitors, TLR7 agonists)
- Infectious Diseases (HIV/SIV, Zika virus)
- Cancer Research (therapeutic vaccines)
Recent publications highlight advances in:
- Viral latency reversal using TLR7 agonists
- CD8+ T cell trafficking to B-cell follicles
- Mucosal immunity for vaginal SIV prevention
- Direct-acting antivirals for Zika virus
- Microbiome interactions in SIV infection
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