James R. Ison

James R. Ison is a Professor in Brain and Cognitive Sciences with joint appointments in Otolaryngology and Neurobiology & Anatomy at the University of Rochester. His research program investigates auditory temporal processing deficits in aging populations using mouse models to bridge neurobiological mechanisms with human presbycusis. Key research areas include auditory gap detection, neural encoding of sound offsets, and sensory-motor integration.

His published work demonstrates how genetic manipulations (e.g., Kcna1 deletion) affect temporal acuity and spatial hearing. Recent studies focus on age-related changes in auditory cortex and glial cells, employing electrophysiological and behavioral techniques to model human hearing decline.