James Broach

James Broach is a Professor at Penn State University, holding dual appointments in the Department of Molecular and Precision Medicine and Department of Otolaryngology - Head and Neck Surgery. He serves as Interim Chair and Director of the Institute for Personalized Medicine, leading initiatives in genomic medicine and contributing to the Penn State Cancer Institute. His work aligns with UN Sustainable Development Goal 3: Good Health and Well-being.

• Research Interests
  • Yeast Saccharomyces as a model organism for studying cell-environment interactions
  • Signaling pathways for nutrient sensing (Ras/protein kinase A, TOR complex)
  • Single-cell stress response heterogeneity and survival strategies
  • Personalized medicine through genomics, biorepositories, and bioinformatics
  • Applications in cancer, ALS, multiple sclerosis, and osteoporosis
• Scientific Awards
  • Career Citation Milestone Award - D (500) Club (2020)
  • Career Citation Milestone Award - M (1000) Club (2017)
• Article Trends
  • Focus on genomic instability, HPV integration, and stress response mechanisms in 2025
  • Recent work bridges yeast signaling studies to clinical applications in leukemia and head/neck cancer
  • Long-term contributions to pathway modeling and big data training programs