Jacob Rube

Jacob Rube, MD is an Assistant Professor of Neurology at the School of Medicine, Wayne State University, where he also serves as Director of the Residency Training Program. His work focuses on clinical neuroimmunology and autoimmune neurological disorders.

• Education:
  • Undergraduate: Touro College (2005-2010)
  • Medical: Wayne State University School of Medicine (2010-2014)
  • Neurology Residency: Northwell Health (2015-2018)
  • MS/Neuroimmunology Fellowship: Wayne State University & Detroit Medical Center (2018-2019)

Dr. Rube's research explores clinical aspects of Multiple Sclerosis and related conditions like NMOSD, MOG Antibody Disease, and Myasthenia Gravis, with a focus on inflammation-driven disability progression and therapeutic innovations. His work includes high-impact clinical trials and studies on neuroimmune interactions in systemic disorders.

Recent Publications span topics such as Brutinib inhibitors in progressive MS, complement inhibition in myasthenia gravis, and obesity's impact on retinal integrity in MS. Earlier nephrology studies reflect cross-disciplinary expertise.