Jacob Høygaard Rasmussen

Jacob Høygaard Rasmussen serves as a Clinical Associate Professor in the Department of Clinical Medicine at the University of Copenhagen's Faculty of Health and Medical Sciences. His research focuses on head and neck oncology, particularly HPV-mediated oropharyngeal cancers, with extensive work on cancer staging, prognosis, and diagnostic imaging techniques.

Dr. Rasmussen's research interests center on the epidemiology, diagnosis, and treatment of head and neck cancers, with particular emphasis on HPV-related oropharyngeal carcinoma. His work explores the prognostic implications of various biomarkers including p16 and HPV status, cancer staging systems, and the application of advanced imaging techniques like 3D ultrasound and MRI for surgical planning. His research bridges clinical practice with epidemiological analysis, examining trends in cancer incidence and outcomes across different populations.

His publication record demonstrates a strong focus on head and neck cancer research with particular attention to HPV-related oropharyngeal cancers. His recent work examines the accuracy of radiologic imaging for assessing cancer spread, risk stratification models for clinical trials, international comparisons of cancer outcomes, and the epidemiological trends of oropharyngeal cancer in high HPV-prevalence regions. His research frequently involves large-scale, multinational collaborations such as the Head and Neck Cancer International Group (HNCIG).

Dr. Rasmussen's work has garnered significant attention in the scientific community, with multiple publications receiving substantial citations and media coverage. His 2023 Lancet Oncology paper on p16 and HPV discordance in oropharyngeal cancer has been particularly influential, with over 180 citations, mentioned in news outlets, social media, Wikipedia pages, and clinical guidelines.

His research activities include participation in clinical diagnostic accuracy studies examining 3D ultrasound and MRI for assessing resection margins during tongue cancer surgery, as well as investigations into the clinical implications of genetic intratumor heterogeneity for targeted therapy in head and neck cancer. His collaborative work spans multiple institutions across Denmark and internationally, reflecting the global significance of his research in the field of head and neck oncology.