Hugues Aschard

Hugues Aschard is a Principal Investigator and Structure Manager at the Pasteur Institute in Paris, where he leads research in statistical genetics, microbiome analysis, and computational genomics. He is the principal investigator of the MicMat project, the EpiGenCOV Consortium, and several bioinformatics software initiatives including JASS, RAISS, and MGMM.

Research Interests:

• Statistical and computational methods in genetics
• Genome-wide association studies (GWAS)
• Gene-environment interactions
• Microbiome and host genetics in inflammatory bowel disease
• Genetic epidemiology of infectious diseases like COVID-19
• Development of open-source tools for multi-trait and summary-statistic analysis

Recent Research Trends: His recent publications and projects emphasize integrative genetic modeling, multi-trait analysis across diverse populations, and the development of novel computational methods to handle missing data and improve SNP discovery. His work bridges statistical innovation with biological and clinical applications in complex diseases.

Scientific Contributions:

• Development of JASS, RAISS, and MGMM software tools
• Leadership in large-scale consortia like EpiGenCOV
• Advancing methods for cross-ancestry genetic studies

Advising and Collaboration: He supervises multiple PhD students and postdoctoral fellows, including Christophe Boetto, Antoine Auvergne, and Lucas Chataigner. He collaborates with major institutions such as APHP and CNRGH. His team includes research engineers and administrative staff, indicating an active and well-supported research group.

Laboratories and Teams: He is a key member of the Biomaterials and Microfluidics team at the Pasteur Institute, where he contributes to interdisciplinary research involving Bayesian decision processes and genetic modeling.