Hugh Clarke

Hugh Clarke, PhD is a Senior Scientist at the RI-MUHC, Glen site and a Professor in the Department of Obstetrics and Gynecology at McGill University's Faculty of Medicine and Health Sciences. His research focuses on oocyte development within ovarian follicles.

Research Interests:

• Oocyte growth and maternal molecule storage
• Germ cell-somatic cell communication
• Environmental toxin effects on oocyte quality
• Intercellular signaling mechanisms
• mRNA regulation during maturation
• Chromatin remodeling at fertilization

Publications (2015-2024) reveal expertise in reproductive biology, with key projects examining:

• EGFR signaling in follicular decoupling
• mTOR pathway in follicle communication
• CNOT6-mediated mRNA deadenylation
• Transzonal projection architecture
• Epigenetic inheritance patterns
• Actin's role in meiotic processes

Location: Lab F3-50, Royal Victoria Hospital, Montreal, QC H3A 1A1