
Howard I. Scher
Professor · Prostate Cancer Research
Memorial Sloan Kettering Cancer CenterAbout
Howard I. Scher, MD is a Professor of Medicine at Weill Cornell Medical College and holds the D. Wayne Calloway Chair in Urologic Oncology. He previously served as Chief of the Genitourinary Oncology Service at Memorial Sloan Kettering Cancer Center (MSKCC) for 25 years. His expertise lies in treating advanced prostate cancer and developing targeted therapies and biomarkers like circulating tumor cell analysis. He leads major initiatives including the Prostate Cancer Clinical Trials Consortium and the NCI-sponsored Prostate Cancer SPORE program. Scher has authored over 430 peer-reviewed articles and co-authored Principles and Practice of Genitourinary Oncology.
His research focuses on androgen receptor signaling, novel imaging modalities, and clinical trial design. Awards include the Donald S. Coffey-Prostate Cancer Foundation Physician-Scientist Award and repeated recognition as a Top Doctor by Castle Connolly. He serves on editorial boards of journals like New England Journal of Medicine and Nature.
Key contributions include standardizing phase II clinical trials for prostate cancer and developing the Clinical States Model to guide treatment. His work integrates basic science with clinical practice, emphasizing translational research to improve patient outcomes.
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