
About
Dr. Hong Wu is a Professor at the David Geffen School of Medicine, University of California, Los Angeles, affiliated with the Department of Molecular & Medical Pharmacology. His research focuses on the molecular mechanisms of tumor suppression, particularly the role of PTEN in cancer development, stem cell regulation, and signal transduction pathways.
- Research Interests: Dr. Wu investigates PTEN's role in tumor suppression, its interactions with signaling pathways like PI3K/AKT and JNK, and its implications in prostate, pancreatic, and other cancers. His work also explores cancer stem cell biology, metabolic vulnerabilities, and translational applications of molecular profiling.
Publications: His work spans studies on PTEN in prostate cancer progression, microRNA biomarkers in pancreatic cancer, and the regulation of stem cell self-renewal. Collaborative efforts include xenograft models, metabolomics, and signaling network analysis.
Collaborations: Dr. Wu collaborates with researchers in oncology, molecular biology, and imaging, including institutions like UCLA, Harvard, and the University of California system.
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