Hilal Arnouk

Hilal Arnouk, M.D., Ph.D., a Professor and Pathology Discipline Lead at The Chicago School's Illinois College of Osteopathic Medicine, specializes in Medical Education. His career spans academia and biotech, focusing on Cancer Immunotherapy, Biomarker Discovery, and Precision Medicine, with a strong emphasis on proteomics and molecular tumor profiling.

• Education:
  • Doctorate, State University of New York at Buffalo
  • Doctorate, Roswell Park Cancer Institute
  • Post-doctoral Fellowship, Medical College of Georgia
  • Post-doctoral Fellowship, University of Alabama at Birmingham

His research leverages laser capture microdissection, differential proteomics, and mass spectrometry to identify tumor antigens and biomarkers for ovarian, breast, and cervical cancers. He pioneers immunotherapeutic strategies targeting glioblastoma multiforme via gamma delta T cell activation, aiming to improve survival rates for aggressive cancers.

Recent publications highlight his work on Cornulin as a biomarker for cutaneous and oral squamous cell carcinomas, alongside studies on PTEN, DJ-1, and EMT pathways in tumor progression. His 2025 book Biology of T Cells in Health and Disease further solidifies his expertise in tumor-immune interactions.

Dr. Arnouk champions an adaptive learning pedagogy, fostering critical thinking and holistic healthcare professionalism. His contributions bridge translational research, clinical utility of biomarkers, and innovative educational frameworks in integrated health sciences.