
About
Hans Haecker is a Professor of Microbiology and Immunology at the University of Utah, with active affiliations to the Molecular Biology Program and the Biological Chemistry Program. His research is centered on innate immunity, inflammation, autoimmunity, hematopoiesis, and drug discovery.
Education:
- M.D. – University of Ulm, Germany
- Ph.D. – Technical University Munich, Germany
Research Focus:
The Haecker lab investigates how innate immune cells detect pathogens and orchestrate inflammatory responses, leveraging proteomics, mouse models, and small-molecule screening to uncover therapeutic targets. Key themes include:
- Toll-like receptor (TLR) signaling: dissecting molecular cascades with quantitative mass spectrometry.
- Inflammatory diseases: building lupus and psoriasis mouse models to study pathogenesis.
- Hematopoietic progenitors: using regulated Hox-genes to immortalize and study immune cell differentiation.
- Drug development: phenotypic screens for novel anti-inflammatory compounds.
Publication Trends:
From 1998 to 2022, his work spans signal transduction, autoimmune pathogenesis, viral-host interactions, and therapeutic innovation, consistently integrating molecular insights with translational applications.
Scientific Awards:
No specific awards are listed in the provided text; however, his extensive publication record in Nature, Science Advances, and other high-impact journals attests to significant recognition.
Advising & Grants:
While individual students are not named, the lab’s robust output and collaborative projects (e.g., multi-author COVID-19 diagnostics paper) indicate active mentorship and well-funded programs.
Laboratory & Teams:
The Haecker Laboratory at the University of Utah maintains a dedicated lab page, a PubMed literature search, and a Twitter presence, reflecting an engaged and collaborative research environment.
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