Guy Moss

Guy Moss is a Reader in Neuroscience at University College London (UCL), affiliated with the School of Neuroscience, Physiology & Pharmacology. His research spans ion channels, transporters, and computational modeling, focusing on airway epithelia and cystic fibrosis (CF) pathophysiology. He collaborates with Paola Vergani, Vivek Dua, and Marco Radi to advance CF therapies through computational and biophysical approaches.

• Doctor of Philosophy (Imperial College London, 1989)
• Postgraduate Diploma (Imperial College London, 1989)
• Bachelor of Science (Imperial College London, 1985)

Moss’s work integrates computational modeling and machine learning to study ion transport systems in airway epithelia, particularly in CF. His research also addresses synaptic transmission in the central nervous system (CNS), including pain pathways. Recent publications highlight multicellular modeling of CF gene therapies and BK channel modulation as a therapeutic strategy.

His 15 most recent outputs reflect trends in CF treatment, ion transport modeling, and nanoscale biophysical methods. Key articles include theoretical frameworks for airway surface liquid homeostasis and BK channel activation as CF targets.

• James Hudson Brown-Alexander B. Coxe Postdoctoral Fellowship
• Patrick and Catherine Weldon Donaghue Postdoctoral Fellowship

Moss contributes to graduate and undergraduate pharmacology education at UCL. He serves as Deputy Director for the London Interdisciplinary Doctoral Programme (LIDo) and teaches modules on drug mechanisms, receptor theory, and molecular pharmacology. His lab collaborates with the Biophysical Society and British Pharmacological Society, supporting research in respiratory and pharmacological sciences.