Guoping Feng

Guoping Feng is the James W. Poitras Professor of Brain and Cognitive Sciences at MIT and Associate Director of the McGovern Institute for Brain Research. He leads the Hock E. Tan and K. Lisa Yang Center for Autism Research and directs the Model Systems and Neurobiology group at the Stanley Center for Psychiatric Research. His work focuses on synaptic mechanisms underlying neurodevelopmental and psychiatric disorders, including autism and schizophrenia, using molecular genetics and electrophysiological methods.

Research Interests: Synaptic function, neurocircuit development, psychiatric disorders, gene therapy, and non-human primate models (e.g., marmosets). Active projects include mapping cellular diversity in the brain and developing genetic tools for neuroscience.

Key Achievements: Pioneered gene-based therapy for SHANK3-related autism, demonstrating reversal of symptoms in animal models. His lab has advanced CRISPR-based technologies and studies thalamic circuitry in Parkinson’s and schizophrenia.

Affiliations: Broad Institute of MIT and Harvard, Simons Center for the Social Brain, and McGovern Institute for Brain Research. The lab emphasizes diversity and inclusion, fostering a collaborative environment.