Guillermo Abascal Palacios

Guillermo Abascal Palacios is a Research Fellow at the Biofisika Institute (CSIC, UPV/EHU), where he holds both a Ramón y Cajal Fellowship and an Ikerbasque Research Fellowship. He leads the Structural Biology of Genomic Macromolecular Complexes Group, focusing on the architecture and function of protein complexes involved in genome regulation, particularly RNA polymerase III and associated transcription factors.

• Bachelor of Science in Biochemistry, University of the Basque Country (2007)
• Master of Science in Molecular Biology and Biomedicine, University of the Basque Country (2008)
• Ph.D. in Biochemistry, CIC-bioGUNE (2013)

His research integrates cloning, expression, chromatography, biophysics, and cryo-electron microscopy (cryo-EM) to determine high-resolution structures of protein-DNA/RNA complexes. He is recognized for his expertise in structural studies of transcription machinery, particularly in eukaryotic systems.

The most recent publications reflect a strong trend in structural and mechanistic dissection of RNA polymerase III and its regulatory complexes, using cutting-edge cryo-EM and biochemical approaches. His work bridges molecular biology, structural biology, and genomics, contributing to understanding fundamental processes in gene expression.

Guillermo has been awarded several prestigious fellowships:

• Marie-Sklodowska Curie Fellow
• Ramón y Cajal Fellow
• Ikerbasque Research Fellow

He has mentored junior researchers and postdoctoral fellows within collaborative projects, though formal advisee names are not listed. His work has been supported by competitive fellowships and institutional funding. He is actively involved in research dissemination and outreach through the Biofisika Institute.

He leads the Structural Biology of Genomic Macromolecular Complexes Group at the Biofisika Institute, which operates within the Science Park of the University of the Basque Country in Leioa, Spain. The group combines structural, biochemical, and biophysical methodologies to investigate macromolecular assemblies central to genome function.