Guillermo A Ameer

Guillermo A Ameer is a Professor at Northwestern University, holding joint appointments in the McCormick School of Engineering and Feinberg School of Medicine's Department of Surgery (Vascular Surgery). He leads research in regenerative engineering, focusing on advanced biomaterials and bioresorbable devices for tissue repair. His work bridges materials science, biomedicine, and engineering, with applications in vascular surgery, bladder regeneration, and wound healing.

Key affiliations include the Simpson Querrey Center for Neurogenetics, Chemistry of Life Processes Institute, and the Northwestern University Clinical and Translational Sciences Institute (NUCATS). His research emphasizes 3D-printed biodegradable scaffolds, smart hydrogels, and wearable medical devices. Notable innovations include:

• Thermoresponsive hydrogels for diabetic wound healing
• Wireless implantable sensors for bladder monitoring
• Citrate-based vascular scaffolds for coronary angioplasty
• Antioxidant biomaterials for islet transplantation

His studies explore how material microstructure (e.g., micropillar geometry) influences stem cell differentiation via nuclear mechanics and chromatin reprogramming. Recent work involves integrating bioelectronic systems with regenerative therapies, such as conductive elastomers for bladder regeneration and stretchable bioresorbable stimulators for neuromuscular repair.

A central theme is transitioning from passive biomaterials to proregenerative systems that actively guide tissue repair. Current projects include developing personalized scaffolds for craniofacial defects and optimizing nanocarriers for immunosuppressive therapies.