Guidalberto Manfioletti

Prof. Guidalberto Manfioletti is a full professor in the Department of Life Sciences at the University of Trieste, specializing in Molecular Biology with a focus on Chromatin and epigenetics in cancer. He serves on the Department's Board and coordinates Doctoral Studies Boards for the Molecular Biomedicine program (Cycles XXX, XXXI, and XXXII).

Research Interests:

• Chromatin architecture in tumor progression
• Epigenetic mechanisms in oncogenesis
• Non-coding RNA regulation of telomeres
• HMGA1 protein in cancer prognostics
• RNA-based therapies for glioblastoma

Scientific Contributions:

• Investigates RNA:DNA hybrids and genomic instability
• Develops tumor organoid models for precision medicine
• Participates in EU-funded projects like National Center for Gene Therapy and Drug Based on RNA Technology
• Active in ARREST project targeting glioma invasion