Guenter Fritz

Guenter Fritz is a Lecturer at the Institute of Biology, University of Hohenheim, with a focus on structural biology and microbiology. He also holds a part-time Senior Scientist position at Expose Data Collection Service GmbH (Swiss Light Source, Villigen, CH).

• Key research areas: Structural biology of redox-driven ion pumps, ISG15/USP18 protease interactions, RAGE signaling in inflammation, and bacterial energy conversion systems.
• Projects: Analysis of FeS cluster assembly in Na+-NQR and RNF complexes (DFG project 311211092), LAPIN (anti-Gram-negative pathogen drug discovery).

His publications highlight structural and functional studies of sodium-pumping enzymes in pathogens like Vibrio cholerae and Prevotella bryantii, amyloid-related proteins in neurodegeneration, and deubiquitinase activity in innate immunity. Current projects include inhibitor development for ISG15-specific proteases using high-throughput screening and crystallography.

• Key collaborations: Swiss Light Source (Villigen, CH), DFG-funded initiatives, and interdisciplinary teams in biochemistry and microbiology.
• Group members: Luise Weber, Sebastian Herdan, Jonatan Vering, Jann-Louis Hau, Mustafa Zeno, Anna-Maria Herzog, Stefan Jäger (contact details provided).