Gregory D. Cascino

Gregory D. Cascino, M.D., is the Whitney MacMillan Jr. Professor of Neuroscience and Enterprise Chair of the Division of Epilepsy at Mayo Clinic College of Medicine and Science. He specializes in neurology with a focus on drug-resistant epilepsy. His clinical work includes advanced neuroimaging, intracranial EEG monitoring, and surgical interventions.

Education:

• M.D., Rush Medical College (1979)
• Residency in Neurology, Harvard Medical School (1985)
• Clinical Fellowship in Neurology, Massachusetts General Hospital/Harvard University (1986)
• B.S. in Biological Sciences, Northwestern University

Research Focus: Dr. Cascino leads studies on cannabidiol therapy, intranasal diazepam rescue protocols, stereotactic laser ablation, and the Epilepsy Genetics Initiative. His work aims to achieve seizure freedom without treatment adverse effects.

Publication Trends: His 346+ publications emphasize epilepsy mechanisms, neuroimaging diagnostics, and genetic underpinnings of seizure disorders, with recent work exploring polygenic risk and neuromodulation.

Awards & Honors:

• President's Award, AAN (2021)
• J. Kiffin Penry Award, AES (2013)
• Alpha Omega Alpha Honor Society (1977)

Professional Leadership: Dr. Cascino chairs committees at the American Academy of Neurology and American Epilepsy Society, driving initiatives in industry relations and epilepsy care standards.