Gopala Rangan

Professor Gopala Rangan is a clinician-scientist at the Westmead Clinical School, University of Sydney, and Head of the Michael Stern Laboratory for Polycystic Kidney Disease at the Westmead Institute for Medical Research. His work focuses on autosomal dominant polycystic kidney disease (ADPKD), the most common genetic cause of kidney failure in adults, and extends to chronic kidney disease, dialysis, and glomerulonephritis.

• Affiliations: Senior Staff Nephrologist, Westmead Hospital; Co-Chair, SONG-PKD consortium; Member, 2021 KDIGO international guidelines for PKD

Research Interests center on translational approaches to ADPKD and genetic kidney diseases, integrating preclinical models (e.g., Vitamin D receptor signaling, NF-κB inhibition) and clinical trials (PREVENT-ADPKD, CKD-FIX). His work emphasizes non-pharmacological interventions like hydration therapy and molecular pathogenesis studies.

Scientific Contributions include leadership in 15+ clinical trials and guidelines, with recent publications highlighting genomic diagnostics (KidGen study), consensus-driven outcomes (KDIGO 2025 guidelines), and nutritional interventions (BEET-PKD, ketogenic diets). Key themes: Healthy Ageing, Cell Biology, and Clinical Trials.

• Awards/Honors: Lead Investigator, PREVENT-ADPKD (GNT1138513); Chair, Scientific Advisory Board of PKD Australia; KDIGO 2025 Guideline Committee member

Advising roles include mentoring students and collaborators on ADPKD, though specific advisees are not listed. Grants: Joint industry-funded PREVENT-ADPKD (GNT1138513), PKD drug development program (GNT1164128).