George Carrum

Dr. George Carrum, M.D., is a Professor at the Center for Gene Therapy of Baylor College of Medicine, Houston, Texas. His clinical and research work focuses on hematopoietic stem cell transplantation (HSCT) for hematologic malignancies and autoimmune diseases.

• Key affiliations:
  • Center for Gene Therapy, Baylor College of Medicine
  • Dan L Duncan Comprehensive Cancer Center member
  • Houston Methodist Hospital clinic

Dr. Carrum's research explores high-dose chemotherapy with stem cell rescue for multiple myeloma, lymphoma, and leukemia, alongside post-transplant immunotherapy and submyeloablative regimens in allogeneic HSCT. His work spans:

• Viral immune reconstitution (CMV, EBV, HHV-6)
• Graft-versus-host disease management
• Cytotoxic T-lymphocyte therapy
• Novel conditioning protocols
• Drug interactions in transplant patients

Analysis of his 37+ publications (1986-2012) reveals trends in allogeneic transplantation for hematologic diseases, adoptive T-cell therapy, and viral complications post-HSCT. His 15 most recent works (2007-2012) emphasize:

• Immunosuppressive drug interactions
• CAR-T cell costimulation
• Viral encephalitis post-transplant
• Autoimmune disease applications
• Salvage therapies for graft failure
• Cytologic diagnostics in transplant complications

Dr. Carrum's clinical practice at Houston Methodist Hospital (6565 Fannin St.) and collaborations with institutions like the Dan L Duncan Comprehensive Cancer Center highlight his role in translational stem cell research and clinical hematology-oncology practice.