Geoffrey Kapler

Geoffrey Kapler, PhD is a Professor in the Department of Cell Biology and Genetics at Texas A&M University's School of Medicine. His research focuses on eukaryotic chromosome replication mechanisms and their role in genome instability linked to cancer. He uses Tetrahymena thermophila as a model system to study replication origin establishment and regulation across cell cycles.

Education:

• BS in Biology, University of Connecticut (1979)
• PhD in Molecular Biology, Harvard University (1989)
• Postdoctoral Training, University of California, San Francisco

Research emphasizes replication initiation site mapping via nascent strand DNA sequencing, ORC/MCM protein dynamics under stress, and unconventional S phase mechanisms. His lab employs advanced techniques including single-molecule DNA fiber imaging and high-throughput sequencing.

Awards: Recognized with Excellence in Research Award from Texas A&M Health Science Center.

Lab Team: Includes Instructor Marcella Cervantes, PhD, and graduate researchers Miguel Gonzalez and Linying Zhang. Active in developing genetic tools for studying DNA replication mechanisms in ciliates.