Geeta Mehta

Geeta Mehta, Ph.D., is an Associate Professor in the Department of Biomedical Engineering at the University of Michigan. Her research focuses on engineered cellular microenvironments using biomaterials and microtechnology to study cancer biology, stem cell engineering, and regenerative medicine. She leads the Engineered Cellular Microenvironments (ECM) Lab and emphasizes interdisciplinary collaboration across materials science, oncology, and biomedical engineering.

Her work addresses critical challenges in ovarian cancer, breast cancer, and bone marrow stem cell research through innovations in bioMEMS, microfluidics, and tumoroid models. Recent studies include mechanotransduction in cancers, personalized tumoroid drug screening, and development of antimicrobial surfaces. She actively explores translational applications, including a phase II clinical trial of metformin targeting cancer stem cells.

• Research Highlights: 3D tumor modeling, cancer stem cell dynamics, mechanobiology of tumors, and antimicrobial biomaterials
• Labs/Teams: Engineered Cellular Microenvironments (ECM) Lab
• Key Collaborations: Cross-departmental work in materials science, oncology, and biomedical engineering

Publications span over two decades, with recent emphasis on tumor microenvironment complexity, chemoresistance mechanisms, and biomaterials innovation. Her research bridges fundamental science and clinical translation, aiming to advance personalized cancer therapies and regenerative strategies.