Frederick Lenz

Frederick Lenz is a Professor in the Department of Neurosurgery at the Johns Hopkins University School of Medicine. His research is centered on the neurophysiological mechanisms of pain, motor control, and brain plasticity, with a focus on direct human brain recordings.

His work bridges clinical neurosurgery and fundamental neuroscience, investigating thalamic and cortical processing of sensory and painful stimuli. Using intracranial recordings from patients with epilepsy or movement disorders, his lab examines functional connectivity, neuronal dynamics, and the neural basis of perception.

The recent publications highlight a strong focus on pain networks, thalamic function, and cortical synchrony, particularly in the context of Parkinson’s disease and chronic pain. His research integrates electrophysiology, neuroimaging, and psychophysics to understand human sensory and motor systems.

• Lesion studies in thalamic pain pathways
• Single-unit recordings in movement disorders
• Pre-stimulus cortical synchrony and pain perception
• Functional imaging before and after cingulotomy

Dr. Lenz leads an active research laboratory with postdoctoral fellows, a technician, and a computer engineer, indicating a robust and collaborative research environment. No scientific awards are listed in the provided text.

He advises trainees and collaborates widely, contributing to both clinical and basic neuroscience literature. His work has implications for neuromodulation therapies and understanding the neural correlates of consciousness and perception.