
About
Frederick Klauschen is a Professor and Director at the Institute of Pathology, Ludwig Maximilian University of Munich, focusing on integrating multi-omics data (genomics, epigenetics, transcriptomics, proteomics) with explainable artificial intelligence (AI) to decode tumor complexity. His lab collaborates with institutions like TU Berlin and Max Delbrück Center for Molecular Medicine (MDC) Berlin.
- Research Highlights
- Digital Pathology & AI: Automated cell nucleus detection, explainable AI for histological heatmaps
- Proteomics: Mass spectrometry for signaling pathway analysis
- DNA Methylation: Epigenetic tumor classification via array and bisulfite methods
- Single-Cell Analysis: Genomic/transcriptomic profiling of individual cells
- Multiplex Immunofluorescence: Spatial tumor cell interaction mapping
Article Trends: His recent work emphasizes AI-driven multimodal data integration (clinical, imaging, molecular) to predict cancer outcomes, with a focus on explainable foundation models and single-cell resolution of tumor heterogeneity. Key collaborations include Prof. Klaus-Robert Müller (TU Berlin) and Dr. Philipp Mertins (MDC Berlin).
- Students & Research Associates
- Yauheniya Zhdanovich (Bioinformatics PhD)
- Edgar Chimal (Research Associate)
- Emma Payá Cipalla (Research Associate)
- Maximilian Leitheiser (Research Associate)
- Christoph Geisenberger (MD, M.Sc.)
- Philipp Keyl (MD, PhD)
- Oliver Buchstab (MD, M.Sc.)
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