Francesco Roselli

Francesco Roselli is an Adjunct Professor at the Center for Biomedical Research, University of Ulm. His work focuses on the hypothalamus's role in neurodegenerative diseases like Amyotrophic Lateral Sclerosis (ALS) and Huntington's Disease (HD), investigating how hypothalamic dysfunction contributes to metabolic disturbances and disease progression.

• Uses viral vectors and AI to map brain-hypothalamus connections in ALS mouse models
• Applies chemogenetic techniques to modulate neuronal subpopulations affecting energy balance
• Develops biomarkers through antibody array analysis of hypothalamic neurochemical changes
• Translates findings via patient sample analysis and clinical trials of energy-dense supplements