Francesco Napolitano

Francesco Napolitano serves as Associate Professor in the Department of Science and Technology (DST) at the University of Sannio, where he leads computational research bridging artificial intelligence and biological systems.

His research program integrates Bioinformatics and Artificial Intelligence to develop computational models for analyzing complex biological systems. Specializing in Systems Biology and Systems Pharmacology, he constructs predictive algorithms that process large-scale -omics data to identify biomarkers and map molecular interactions. Key research domains include computational drug discovery (using molecular interaction networks for target identification and drug repurposing), biological pathway modeling, diseasome analysis for understanding pathogenic mechanisms, and multi-omics integration (genomics, transcriptomics, proteomics, metabolomics) to model cellular dynamics under pharmacological perturbations. Machine Learning techniques form the backbone of his approach to extracting meaningful patterns from complex biological datasets.

Dr. Napolitano directs research activities at BioinfoLab, where his team develops systemic representations of cellular responses to environmental and therapeutic interventions, contributing to personalized treatment strategies through advanced computational modeling.