Felix Marsh-Wakefield

Felix Marsh-Wakefield is an Adjunct Lecturer at the University of Sydney, affiliated with the School of Medical Sciences within the Department of Medical Sciences at the Faculty of Medicine and Health. He is also a member of the Charles Perkins Centre, indicating his involvement in interdisciplinary research focused on health and medical sciences.

His research primarily centers on immunology with specific focus on multiple sclerosis, blood-brain barrier pathologies, T-cell biology, and cytometry data analysis. His work spans both computational and experimental approaches, developing tools for high-dimensional cytometry data analysis while investigating immune mechanisms in autoimmune diseases and cancer. His research demonstrates strong interdisciplinary connections between immunology, neurology, and computational biology.

Analysis of his recent publications reveals a consistent focus on immune cell dynamics in multiple sclerosis, with particular attention to T-cell and B-cell behavior across the blood-brain barrier. His work also extends to cancer immunology, particularly hepatocellular carcinoma, and methodological advancements in cytometry data analysis. The publications demonstrate expertise in both wet-lab immunological techniques and computational approaches to complex immune datasets.

Dr. Marsh-Wakefield has received research funding including a 2024 Early Career Researcher Grant from Tour de Cure Ltd for a project titled 'Using spatial transcriptomics to identify immune cell interactions associated with tumour recurrence in hepatocellular carcinoma'.

He currently supervises at least one research student, Linda LIN, who is working on 'Immune mechanisms of blood-brain barrier pathologies'. His laboratory work appears to focus on immune cell migration, particularly across the blood-brain barrier, and the development of computational tools for analyzing complex immune datasets.