Fei Yin

Fei Yin is an Associate Professor in Pharmacology at the University of Arizona, with a research focus on molecular and cellular mechanisms of neurodegeneration, particularly in Alzheimer's disease. Their work integrates lipid metabolism, mitochondrial dysfunction, and neuroinflammation within the context of APOE4 genotype and sex-specific risk factors.

Key research themes include:

• Lipid-centric models of Alzheimer's pathogenesis
• Neuroimmune interactions during aging
• Metabolic reprogramming in neurodegenerative contexts
• Interplay between mitochondrial genetics and hormonal status

Recent publications highlight therapeutic strategies targeting mitochondrial dysfunction and metabolic interventions (e.g., methionine restriction, high-fiber diets) to mitigate cognitive decline. Their work spans both basic science and translational approaches.

Scientific recognitions include:

• 2019 Bio5 Institute Team Scholars Award
• 2017 Packer Wentz Endowment funding
• 2014 Linus Pauling Institute Young Investigator Award

The Yin Laboratory develops novel therapeutics by restoring lipid homeostasis and investigates maternal mitochondrial DNA effects on brain metabolism and disease risks.