Farhat Din

Farhat Din is a Principal Investigator and Honorary Consultant Colorectal Surgeon at the Institute of Genetics and Cancer, University of Edinburgh. Her research focuses on metabolism and energy signaling in colorectal cancer, targeting the mTOR pathway to develop chemopreventive agents like aspirin.

• Doctor of Medicine (University of Edinburgh, 2007)
• Bachelor of Medicine and Surgery (University of Manchester, 1996)
• Bachelor of Science (University of St Andrews, 1993)

Her research explores:

• mTOR signaling in cancer cell survival and metabolism
• Molecular mechanisms of aspirin's anti-tumor effects
• Epigenetic regulation and genetic risk factors in colorectal cancer
• Role of colonic tuft cells and metastasis

Recent studies investigate methylation QTLs, early-onset trends in Scotland, and R1 margin impacts in stage III colon cancer. Her work emphasizes pathway-targeted therapies and translational research.

• Cancer Research UK Clinician Scientist fellowship
• Projects funded by CRUK, Bowel Cancer UK, and Royal College of Surgeons

She leads the Metabolism & Energy Signalling in Colorectal Cancer group and collaborates with researchers like Malcolm Dunlop and Susan Farrington. Her clinical practice integrates with her translational research program.