About
Fabio Zanini is an Associate Professor at the University of New South Wales (UNSW), leading a research group focused on computational biology, single-cell approaches, and transcriptomic analysis across diseases like severe dengue, neonatal lung disease, cancer, and marine biology. He previously conducted postdoctoral research at Stanford University (2016-2019) and earned a PhD in Bioinformatics from the Max Planck Institute for Developmental Biology and the University of Tuebingen (2015).
- Current Affiliation: Group leader, UNSW
- Previous Training: Postdoc (Stanford), PhD (Max Planck/University of Tuebingen)
His research spans single-cell RNA sequencing, computational virology, developmental cell biology, and bioinformatics tool development, with recent work on:
- Severe dengue progression (viral-host interactions, immune signatures)
- Lung development (endothelial cell diversity, hyperoxia-induced injury)
- Cancer genomics (mutant HSC clones, AZA therapy response)
- Marine biology (plankton transcriptomics, evolutionary analysis)
- Bioinformatics (HTSeq 2.0, northstar algorithm)
Recent scientific awards include grants from the Chan Zuckerberg Initiative ($270,000), NIH R01 (multiple), ARC Discovery Grant, and NHMRC Ideas Grant. Notable contributions include:
- Northstar - Cell classification algorithm
- SpectralSeq - Hyperspectral-transcriptomic integration
- Tabula Muris - Mouse aging atlas
He has supervised research into hematopoietic stem cell regulation, lung vascular development, and autophagy in viral infections, with collaborations across Stanford, University of Sydney, and Harvard.
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