Félix Rey

Félix Rey is a leading Research Professor at the Structural Virology Unit within the Virology Department of the Institut Pasteur in Paris, France. He spearheads multidisciplinary studies on viral and cellular membrane fusion mechanisms, with a focus on emerging viruses such as Chikungunya, Dengue, and SARS-CoV-2.

His research explores:

• Structural biology of virus envelope glycoproteins (e.g., Chikungunya p62-E1, Hepatitis C E2, Foamy virus Env).
• Molecular interactions in viral entry and neutralization.
• Cell-cell fusion mechanisms in fertilization and development.

Recent publications highlight structural insights into:

• 2025: SARS-CoV-2 spike protein conformational dynamics and ACE2 receptor interactions.
• 2024: Foamy virus fusion protein evolution, TMPRSS2's role in HKU1 coronavirus entry.
• 2023: Yellow fever virus maturation, pan-hantavirus neutralization antibodies.

He collaborates with teams across France, Southeast Asia, and West/Central Africa through the Pasteur International Center for Research on Emerging Infectious Diseases. Current advisees include Paul Courrieu and Marius Allombert (Master's students).