
About
Prof. Dr. Eva Kiermaier leads the Immunology and Tumor Biology department at the Life & Medical Sciences Institute (LIMES) of the University of Bonn. Her research focuses on cytoskeletal components like centrosomes and microtubules in immune cell functions, particularly dendritic cells' roles in antigen presentation, migration, and T cell activation. She investigates how these structures enable immune cells to navigate complex environments and mediate adaptive immunity.
Her work combines in vitro assays with live-tissue imaging and genome editing techniques. Notable contributions include studies on centrosome dynamics in immune cell navigation, microtubule regulation of immune synapse formation, and chemokine-guided dendritic cell trafficking. Her group also explores centrosome amplification's impact on immune effector functions and B cell development.
Key collaborations include projects with the Bonner Forum Biomedizin and the LIMES Institute's transdisciplinary research units. Her recent studies highlight centrosome integrity's role in efficient cell migration, while older work has addressed p27 mutations in endocrine tumors.
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