Eunhee Yi

Eunhee Yi is an Assistant Professor in the Department of Physiology at Michigan State University (MSU). Previously, she held positions at Yale University's Neurosurgery Department as research faculty and completed postdoctoral training in Cancer Genomics at the Jackson Laboratory for Genomic Medicine. She earned her Ph.D. in Biomedical Science from Seoul National University School of Medicine.

Her research focuses on understanding extrachromosomal DNA (ecDNA) mechanisms in cancer progression, particularly its role in treatment resistance, metabolic reprogramming, and cell-to-cell communication. The Yi Lab employs multidisciplinary approaches including molecular/cell biology, genome engineering, live-cell imaging, and high-throughput screenings. Key areas of investigation include ecDNA regulation, cancer heterogeneity, and drug resistance pathways.

Recent publications highlight ecDNA's impact on glioblastoma treatment strategies, CRISPR-based screening of cancer drivers, and the development of targeted therapies like tubulosine. Her work bridges basic molecular mechanisms with translational oncology, emphasizing ecDNA's dynamic role in tumor evolution and therapy response.

While no scientific awards are explicitly listed, her contributions to ecDNA research are highly impactful in cancer biology. Advising and grant information are not detailed in the provided text. The Yi Lab collaborates across disciplines to advance precision cancer medicine and genomic analysis methodologies.