Erica M. Selva

Erica M. Selva is an Associate Professor in the Department of Biological Sciences at the University of Delaware, serving as the Graduate Program Co-Director. She holds affiliations with the College of Arts & Sciences and conducts research in developmental biology using Drosophila melanogaster as a model system.

Education: B.S., Cornell University; Ph.D., University of Massachusetts Medical School; Postdoctoral training at Harvard Medical School.

Research focuses on posttranslational modifications (e.g., glycosylation) and their roles in regulating extracellular signaling pathways critical for development and disease. Key projects investigate Hedgehog (Hh), Wnt/Wg, and Notch signaling pathways, with implications for cancer biology. Her work combines genetic screens, biochemical assays, and tissue culture models to elucidate mechanisms of signaling modulation.

No specific articles were explicitly listed in the provided text, but her research emphasizes novel mutants (7E4, 7H24, 8J16) and modifiers of signaling pathways. Current projects include biochemical characterization of fringe connection (frc) and brainiac (brn) in Notch signaling.

Advising includes mentoring graduate students (e.g., Babak Basiri on Wntless/Wg morphogens) and undergraduates (e.g., Alicia Liu on O-xylosyltransferase function). Research utilizes Drosophila genetics, RNA interference, and cellular trafficking studies.