Eneida R. Nemecek

Eneida R. Nemecek, M.D., serves as Medical Director for Clinical Research at the OHSU Knight Cancer Institute and practices at OHSU Doernbecher Children's Hospital. She specializes in pediatric cancers and bone marrow transplantation, leading national collaborations through organizations including the Children's Oncology Group, Pediatric Blood and Marrow Transplant Consortium, and Center for International Blood and Marrow Transplant Research to advance clinical trials for innovative treatments.

Her educational credentials include:

• B.S. (1992) from University of Puerto Rico
• M.D. (1996) from University of Puerto Rico School of Medicine
• M.S. (2004) from University of Washington
• M.B.A. (2013) from Oregon Health & Science University
• Pediatrics Residency at Rainbow Babies and Children’s Hospital (1999)
• Pediatric Hematology/Oncology Fellowship at Fred Hutchinson Cancer Research Center (2002)

Dr. Nemecek's research centers on graft-versus-host disease mechanisms, cellular therapies, and healthcare disparities in pediatric oncology. Her work addresses critical gaps in understanding steroid-refractory chronic GVHD while investigating sociodemographic barriers to advanced therapies like CAR T-cell treatment. She employs metabolomic and genetic approaches to identify novel biomarkers and therapeutic targets, with emphasis on equitable access to transplantation and emerging immunotherapies for vulnerable pediatric populations.

Analysis of her 15 most recent publications (2020-2025) reveals dominant themes in graft-versus-host disease management (60% of works), particularly pediatric chronic GVHD diagnostics and novel therapeutics like ibrutinib. Significant focus also addresses healthcare disparities in cellular therapy access (20%) and genetic drivers of pediatric leukemias (13%). Her research consistently bridges laboratory discoveries with clinical applications through large consortium trials, demonstrating leadership in standardizing transplant terminology and managing immunotherapy toxicities.

Dr. Nemecek actively contributes to national initiatives through the ASTCT-NMDP ACCESS Initiative, Children's Oncology Group, and Bone Marrow Transplant Clinical Trials Network. These collaborations enable her to direct clinical trials at OHSU Doernbecher Children's Hospital, focusing on innovative cellular therapies and transplantation protocols while addressing systemic barriers to care for pediatric cancer patients.