Elizabeth Gray

Elizabeth Gray is an Associate Professor in the Department of Clinical Neurosciences at the University of Oxford, affiliated with the Oxford Motor Neuron Disease Centre. Her research focuses on biomarker discovery and neurodegenerative disease mechanisms in amyotrophic lateral sclerosis (ALS).

Her work spans proteomic and metabolomic analyses of cerebrospinal fluid (CSF) to identify novel biomarkers such as TDP-43 fragments, neurofilament light chain, and chitotriosidase. These studies aim to enhance early diagnosis, monitor disease progression, and elucidate molecular pathways in ALS.

• Key Themes: ALS pathogenesis, clinical neurology, protein homeostasis, oxidative stress, extracellular vesicles, and neurofilament dynamics.
• Collaborations: Kevin Talbot, Martin Turner, Alexander Thompson.