Eileen Shore

Eileen Shore, PhD, is a Professor of Orthopedic Surgery with a focus on bioinformatics, bone disorders, human genetics, and genomics. Her work explores the molecular mechanisms of fibrodysplasia ossificans progressiva (FOP), a rare genetic condition causing heterotopic ossification.

Research interests center on dysregulated BMP signaling, genetic mutations in ACVR1, and therapeutic strategies for FOP. She has contributed to studies on palovarotene efficacy, gene delivery methods, and the role of activin A in disease progression.

Her publications highlight interdisciplinary approaches combining molecular biology, genetics, and orthopedic research. Key trends include understanding mutation-driven signaling pathways, developing animal models, and investigating pharmacological interventions for heterotopic ossification.