
Edgar T. Walters
Professor · Nociceptor mechanisms
The University of Texas Health Science Center at HoustonAbout
Edgar T. Walters, PhD, is a Professor at The University of Texas Health Science Center at Houston (UTHealth Houston), holding the Fondren Chair in Cellular Signaling and serving as a Ray A. and Robert L. Kroc Faculty Fellow. His research investigates nociceptor hyperexcitability mechanisms in chronic pain, employing electrophysiological, molecular, and behavioral methods across species. Key affiliations include UTHealth Houston, with a focus on translational insights into spinal cord injury, chemotherapy neuropathy, and evolutionary pain adaptations.
Research Focus: Walters explores cellular signaling pathways (cAMP, ERK) and ion channels (TRPV1, Na⁺/Ca²⁺) that sustain nociceptor hyperactivity. His interdisciplinary approach integrates:
- In vivo injury models (surgery, spinal trauma)
- In vitro electrophysiology of isolated neurons
- Comparative biology (humans, rodents, invertebrates)
- Pharmacological targeting of pain mechanisms
Awards and Honors:
- Fondren Chair in Cellular Signaling
- Ray A. and Robert L. Kroc Faculty Fellowship
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