Duilio Cascio
Adjunct Professor · Structural Biology
University of California, Los AngelesAbout
Dr. Duilio Cascio is an Adjunct Professor of Biological Chemistry at UCLA's David Geffen School of Medicine. His research specializes in structural biology approaches to study protein misfolding diseases, bacterial pathogenesis, and development of crystallographic methods.
Key contributions include pioneering work on amyloid structures in neurodegenerative diseases using MicroED, structural characterization of bacterial virulence factors, and integration of AlphaFold predictions with experimental structural biology. His laboratory develops advanced techniques for determining challenging macromolecular structures.
Dr. Cascio's research has illuminated mechanisms of amyloid formation in Alzheimer's and Parkinson's diseases, with recent work extending to bacterial heme acquisition systems and hybrid AI-experimental structure determination.
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