Douglas R. Seals

Douglas R. Seals is a Distinguished Professor in Integrative Physiology at the University of Colorado Boulder. His research investigates cardiovascular aging mechanisms and interventions.

Education includes B.S. degrees from William Jewell College and M.S./Ph.D. from the University of Wisconsin-Madison, with postdoctoral training at Washington University.

Research focuses on age-related changes in vascular function, including arterial stiffness, endothelial dysfunction, and oxidative stress. The Integrative Physiology of Aging Laboratory examines exercise, dietary, and pharmacological interventions to improve cardiovascular healthspan.

Honors include NIH MERIT Award and designation as CU Distinguished Professor. Professional contributions include editorship of Exercise and Sport Sciences Reviews and NIH study section leadership.

Current projects explore senolytic treatments for vascular aging, mitochondrial mechanisms, and lifestyle modification clinical trials.