Douglas J. Demetrick

Douglas J. Demetrick serves as a Professor in the Department of Medical Genetics at the University of Calgary, where he maintains an active research program bridging molecular biology and clinical cancer applications.

With dual doctoral credentials (M.D. and Ph.D.), his expertise spans clinical medicine and fundamental research. His laboratory investigates critical cancer mechanisms through three interconnected research pillars:

• Epigenetic regulation via cytosine methylation/demethylation in breast cancer
• Functional specialization of INK4 proteins in cell cycle control
• Molecular biomarkers for cancer progression and treatment response

Professor Demetrick's work integrates molecular diagnostics with basic cancer biology, focusing particularly on hypoxia responses and genetic markers that could transform diagnostic approaches. His research in epigenetic mechanisms and cell regulation provides foundational insights for developing targeted cancer therapies and precision medicine applications.