About
Professor Derek Mann serves as an Affiliate Professor within the School of Cancer Sciences, contributing to high-impact cancer research as evidenced by recent publications in Nature (2023, 2025). His work bridges molecular oncology and clinical applications, focusing on liver cancer therapeutics and cellular senescence mechanisms.
Research interests prioritize Cancer Research, Liver Cancer, Senescence, Molecular Biology, and Precision Medicine. Mann investigates genetic models for targeted liver cancer therapy and mitochondrial DNA dynamics in senescence, employing molecular diagnostics to uncover therapeutic targets. His approach integrates fundamental cell biology with translational oncology to address therapy resistance.
Publication analysis (2023-2025) reveals a cohesive focus on molecular drivers of cancer progression, particularly mtDNA release in senescence and precision therapy development for liver cancer. These studies establish critical links between apoptotic stress, the senescence-associated secretory phenotype (SASP), and genetic models for personalized treatment, advancing oncology through mechanistic insights.
